What specific birth defects can be caused by Valsartan (Diovan)?!
Question: What specific birth defects can be caused by Valsartan (Diovan).?
The package insert says it can cause birth defects but doesn't say what kind of defects. Does it cause heart problems.? Does it cause something less severe.? What medication can replace it if a wonam wants to have a child.?Health Question & Answer
Answers:
"There have been cases of reported oligohydramnios, fetal growth retardation, pulmonary hypoplasia, limb contractures, and calvarial hypoplasia in various combinations in association with maternal losartan, candesartan, valsartan, or telmisartan (all ARBs) treatment during the second or third trimester of pregnancy. Stillbirth or neonatal death is frequent in these reports, and surviving infants may exhibit renal damage. These effects are probably related to extreme sensitivity of the fetus to the hypotensive action of these drugs."
There are other anti-hypertensive agents that are commonly used during pregnancy. Hydralazine is a common one.
I hope this helps. Good luck.Health Question & Answer
There are other anti-hypertensive agents that are commonly used during pregnancy. Hydralazine is a common one.
I hope this helps. Good luck.Health Question & Answer