If you have the sickle cell trait and have iron deficiency, what does that mean?!


Question: If you have the sickle cell trait and have iron deficiency, what does that mean.?
My father has a miner case of sickle cell and i think i have the trait and i have iron deficiency anemia. Health Question & Answer


Answers:
well sickle-cell trait means you're a carrier, not a sickler, you shouldn't worry about anything rather than be selective when it comes to your future husband cuz of the possibility of passing genes down to ur unborn children.

In the mean time, you have nothing to worry about, iron deficiency is a separate issue you could work it out with your doctor and try to adjust your diet by eating fortified cereals, more red meat, and not taking tea right after meals.

best of luck,Health Question & Answer

It is likely that he has passed it on to you if your mother carries the trait. You can pass this on to your children if the father carries the trait. Which means they can become very sick. Since you only have the trait you have nothing to worry about. However, since you have an iron deficiency you should take iron supplements but consult your doctor because too much iron can be lethal. Eating more red meat, beans will help to naturally boost your iron levels.

Iron deficiency anemia just means that you are anemic and you should supplement your diet with vitamins and foods that are iron rich such as red meats and beans. Health Question & Answer

Individuals with sickle cell trait are generally asymptomatic and have no abnormal physical findings. Their laboratory evaluation is normal with no anemia, no evidence of hemolysis, and no laboratory abnormalities other than hemoglobin AS on hemoglobin electrophoresis. Many individuals will have decreased ability to concentrate their urine. There may be an increased incidence of urinary tract infection during pregnancy. Painless hematurea does occur in 1 to 4 % of individuals with sickle cell trait . This complication is usually not a significant problem, however, a minority of individuals may have significant problems with recurrent hematurea requiring medical intervention, transfusion, and iron therapy. Complications such as splenic infarction, pain episodes, and sudden death may be induced by severe hypoxia, severe dehydration, and exertion at the limits of human endurance.


Clinical Findings

Subjective Data

Present Illness. No symptoms

Past Medical History No medical problems

Family History. Document history of sickle hemoglobin, thalassemia, and other hemoglobin variants.

Review of Symptoms. Asymptomatic

Objective Data

Physical Examination

* Physical examination is normal.

Laboratory

* Minimum Lab. CBC with reticulocyte count. Hemoglobin electrophoresis.
* Additional lab. None

Differential Diagnosis

* Sickle Cell Trait - The individual has no symptoms or physical findings that can be attributed to sickle cell trait. The diagnosis of sickle cell trait is established by an electrophoresis, isoelectric focusing or HPLC result that shows hemoglobin AS with about 55% hemoglobin A and 45% hemoglobin S. Hemoglobin, reticulocyte count and all laboratory tests are normal with sickle cell trait.
* Sickle Beta Plus Thalassemia - The individual with sickle beta plus thalassemia may have symptoms of sickle cell disease. Physical findings can include splenomegaly, retinopathy, avascular necrosis and other sickle cell complications. The hemoglobin may be normal or reduced, but the mean corpuscular volume is almost always reduced and the reticulocyte count is elevated. Elevated lactic dehydrogenase and indirect bilirubin levels are common. The diagnosis of sickle beta plus thalassemia is established by an electrophoresis, isoelectric focusing or HPLC result that shows hemoglobin SA with about 5 to 25% hemoglobin A and 65 to 90% hemoglobin S with elevated hemoglobin A2 and F.
* Sickle plus some other interacting hemoglobin structural variants. Individuals with hemoglobin SC disease are occasionally told that they have sickle trait by uninformed health professionals. Hemoglobin evaluation should be repeated if individuals with "trait" are symptomatic, anemic, or have evidence of hemolysis.

* Sickle Trait No therapy is required
* Sickle beta thalassemia and other Compound heterozygotes These are treated as sickle cell disease.
* Hematuria in Sickle Trait Microscopic or gross hematuria is an uncommon problem in individuals with sickle cell trait occurring in 1 to 4 % of individuals with Hb AS. When it occurs, it tends to be recurrent and can be severe and persistent. Iron deficiency, renal obstruction, infection, and other complications occur.

Treatment first requires a complete evaluation to exclude other causes of hematuria including cystitis, bladder, and renal tumors. Urine culture is always indicated. There is some evidence that medullary carcinoma of the kidney is more common in individuals with HB AS.

Initial treatment includes bed rest, vigorous oral hydration, administration of sodium bicarbonate to alkalinize the urine and diuretics and potassium if required. Individuals with persistent are admitted for strict bed rest and intravenous hydration with alkaline diuresis. Urologic intervention may be beneficial, however, nephrectomy to control bleeding is almost never indicated because of the high probability of recurrence in the contralateral kidney.

Nursing Considerations
* Educate the carrier about the nature of sickle cell trait.
* Provide counseling of the risks of having children with sickle hemoglobin disorders.
* Inpatients with hematuria, monitor the patient fluid intake and output carefully, if fluid or sodium retention develops the doctor may order diuretics.
* Tell carriers to use caution during very strenuous exercise in hot weather or at high altitude. Inadequate fluid intake, and excessive perspiration can lead to dehydration with risk of splenic infarct or hematurea.
* Stress to the patient to continue taking the drug even when he feels better.
Health Question & Answer

I think you are considering if or when your father has transfusions
that his blood has the ability to be iron overload and the doctors tell your father not to take iron pills.

Since you have the trait this has nothing to do with you.
You should probably take an iron supplement
however
always ask your doctors.

I have sickle cell anemia and unfortunately there is no such case of sickle cell disease being miner. Your father may not be affected by crises and other symptoms that normally is caused by sickle cell; not- yet.

I have heard and witness a person with the trait experiencing pain but the pain was not severe as a regular crises caused by sickle cell. This is very rare but now being looked into.

If you are uncertain that you have the trait get tested, usually there are blood drives that may have sickle cell screening and if so it will be free.
Having the trait only means you have the potential to reproduce a child having sickle cell.
You are
sickle cell trait (SN)
"Normal" (NN)
sickle cell anemia (SS)

sickle cell trait (SN) + normal (NN) = 50% sickle cell trait
50% normal (NN)

sickle cell trait (SN) + sickle cell trait (SN) =
25% sickle cell disease (SS)
50% sickle cell trait (SN)
25% normal (NN)

sickle cell trait(SN) + sickle cell disease (SS) =
50% sickle cell disease (SS)
50% sickle cell trait (SN)

iron deficiency and sickle cell trait are not connected.
Health Question & Answer



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