do you know if there is any cure for Marburg virus,or a knownh vaccine, or meda!


Question: I am reading a excellant book the Hot Zone which deals with the marburg and such viruses,but it is a old book,at which a very limited amount of information was given, and there was no vaccine, or cure it has really sparked my curiousity,if any one could answer my question or any other infromation about the virus.
Answers:
As with other hemorrhagic fever viruses, the treatment options for Marburg are limited. Hypotension and shock may require early administration of vasopressors and hemodynamic monitoring with attention to fluid and electrolyte balance, circulatory volume, and blood pressure. Viral hemorrhagic fever (VHF) patients tend to respond poorly to fluid infusions and rapidly develop pulmonary edema.

Patient caregivers require barrier infection control measures including double gloves, impermeable gowns, face shields, eye protection, and leg and shoe coverings.

A few research groups are working on drugs and vaccines to fight the virus. In 2002, Genphar, a company doing research for the United States Army's biodefense program, announced that an experimental vaccine protected animals from a high dose of Marburg virus. The tests were conducted by the United States Army Medical Research Institute of Infectious Diseases (USAMRIID). According to the company, all animals in the control group died within days whereas all animals that received the regular dosage of the vaccine were fully protected. The company has moved on to non-human primate trials. [4] Late in 2003, the US government awarded the company a contract worth $8.4 million for what was described as "a multivalent Ebola, Marburg filovirus vaccine program".

In June 2005 scientists at Canada's National Microbiology Laboratory announced that they had also developed vaccines for both Marburg and Ebola that showed significant promise in primate testing. Studies on mice also suggested that the vaccine might be an effective treatment for the disease if it is administered shortly after a patient is infected. To make the vaccines the scientists fused a surface protein from the viruses they hope to protect against onto an animal virus - vesicular stomatitis - which is thought to be of no threat to humans. [5]

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